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Similarly, untreated type 2 diabetes mellitus is associated with decreased expression of occludin (Chehade et al., 2002) and increased vascular permeability (Sheikh et al., 2022)

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126 While the roles of traditional macrophage subsets like KCs in liver regeneration have been well-documented, recent research has begun to shed light on the diverse and dynamic nature of the macrophage pool, particularly how it evolves from birth through repeated injury and regeneration cycles

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